Hollyoaks is a long-running Channel 4 soap opera in the United Kingdom. This is a list of characters who first appeared on the programme during 2010, listed in order of their first appearance. In January 2010, it was announced that Paul Marquess would be taking over the role of series producer from Lucy Allan, who had been with the valentine rose day for one year. Marquess fully took control on 17 January 2010, onwards.

When Hannah falls off a podium, Jamie catches her and they begin to develop feelings for each other. Jamie tells Hannah that he is no longer dealing drugs, however Hannah asks him to leave. Hannah tells Jamie to leave before Rhys finds him. Rhys tells Jamie to stay away from Hannah. Jamie then calls Hannah and tells her that he loves her.